Endogenous Candida Endophthalmitis: Who is Really at Risk?

The Infectious Disease Society of America recommends that all patients with candidemia undergo a dilated retinal exam to exclude endogenous Candida endophthalmitis. The objective of this project was to determine if there are significant risk factors in candidemic patients for developing endogenous Candida endophthalmitis. 

Compiling Observational Research During a Pandemic: A Necessary Bridge

Dr. Rebekah Moehring and Dr. Thomas Holland talked with Clinical Infectious Diseases Journal about compiling observational research ruring a pandemic. 

Impact of preoperative chlorhexidine gluconate (CHG) application methods on preoperative CHG skin concentration

Led by DCASIP Clinical Ressearch Coordinator (CRC) Bobby Warren, along with CRC Alicia Nelson and Medical Director Dr. Dev Anderson, a team from multiple medical centers in the CDC Prevention Epicenters Program worked to find the impact of preoperative chlorhexidine gluconate (CHG) application methods on preoperative CHG skin concentration. 

Measuring the impact of continuous disinfection strategies on environmental burden in outpatient settings: a prospective randomized controlled trial

The primary objective of this study by the CDC Epicenters Program, led by DCASIP Clinical Research Coordinator Bobby Warren, was to determine the effectiveness of two enhanced disinfection strategies compared to standard disinfection: “near-UV” light (Arm 1) and a persistent organosilane quaternary ammonium disinfectant (Arm 2) using a triple-blind study design. The secondary objective was to characterize environmental contamination of outpatient clinics.

Tap Water Avoidance Decreases Rates of Hospital-Onset Pulmonary Nontuberculous Mycobacteria

Combined efforts from DCASIP faculty, led by Dr. Art Baker, with faculty from the Infectious Diseases Divisions at Duke University Medical Center and the Durham VA Hospital resulted in the latest publication in the journal Clinical Infectious Diseases: Tap Water Avoidance Decreases Rates of Hospital-Onset Pulmonary Nontuberculous Mycobacteria (link to the abstract).

Healthcare associated diarrhea, not Clostridioides difficile

Dr. Nick Turner et al. worked together on an article published in Current Opinion in Infectious Diseases regarding healthcare-associated diarhhea (HCAD). The link to the listing is available here

Navigating Reflex Urine Culture Practices in Community Hospitals: Need for a Validated Approach

The DICON and DASON teams, lead by visiting fellow Dr. Dorothy Ling, performed a descriptive study of reflex urine culture (RUC) practices across 51 community hospitals in southeastern United States. They found that 26 unique reflexing criteria were used in 28 hospitals. Only 14% hospitals of hospitals that offered RUC restricted it to specific populations (e.g. emergency room). The data suggest that the current RUC approach in community hospitals warrants further validation of urinalysis criteria and identification of specific populations in which RUC performs best.

Policies and Practices of SHEA Research Network Hospitals During the COVID-19 Pandemic

Dr. Deverick Anderson worked with a team from several other faclities to review the policies and practices of SHEA research network hospitals during the COVID-19 pandemic for an article published in Infection Control & Hospital Epidemiology. 

Staphylococcus aureus Prostatic Abscess in the Setting of Prolonged S. Aureus Bacteremia

Dr. Emily M. Eichenberger et al have published a case report in Case Reports in Infectious Diseases. 

Efficacy of UV-C disinfection in hyperbaric chambers

Clinical Research Coordinator, Bobby Warren, worked with Drs. Becky Smith, Dev Anderson, and Nick Turner and staff from Duke Center for Hyperbaric Medicine and Environmental Physiology and NC School of Science and Mathematics to measure the efficacy of UV-C disinfection in hyperbaric chanbers in Infection Control & Hospital Epidemiology.