CDC AMR Challenge

The U.S. government’s Antimicrobial Resistance (AMR) Challenge is a yearlong effort to accelerate the fight against antimicrobial resistance across the globe that launched at the United Nations General Assembly in September 2018. 

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DCASIP Programs and Services

The Center’s efforts to improve, explore, educate, and discover strategies to make healthcare safer is made possible through the Center’s four arms of education, consulting, Duke Hospital services, and research.
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We Are Antimicrobial Stewards

We work to prevent antimicrobial resistant infections within the Duke Health system, in community hospitals across the country, and throughout the world through education, research, and consulting. 

Center News

Impact of Education and Data Feedback on Antibiotic Prescribing for Urinary Tract Infections in the Emergency Department: An Interrupted Time Series Analysis

The ASET team led a study on antibiotic prescribing for UTIs in emergency departments published in the journal Clinical Infectious Diseases. 

Urinary tract infections (UTIs) are often misdiagnosed or treated with exceedingly broad-spectrum antibiotics, leading to negative downstream effects. We aimed to implement antimicrobial stewardship (AS) strategies targeting UTI prescribing in the emergency department (ED).

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SARS-CoV-2 Environmental contamination in hospital rooms is uncommon using viral culture techniques

Our lab team, led by Director Bobby Warren, assessed environmental contamination of inpatient rooms housing COVID-19 patients in a dedicated COVID-19 unit. Contamination with SARS-CoV-2 was found on 5.5% (19/347) of surfaces via RT-PCR and 0.3% (1/347) of surfaces via cell culture. Environmental contamination is uncommon in hospitals rooms; RNA presence is not a specific indicator of infectious virus. The team's findings can be found in Clinical Infectious Diseases.

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Impact of Education and Data Feedback on Guideline-Concordant Prescribing for Urinary Tract Infections in the Outpatient Setting

Urinary tract infections (UTIs) are the most common outpatient indication for antibiotics and an important target for antimicrobial stewardship (AS) activities. With The Joint Commission standards now requiring outpatient AS, data supporting effective strategies are needed.

Clinicians increased guideline-concordant prescribing, reduced UTI diagnoses, and limited use of high-collateral damage agents following this outpatient AS intervention. Routine data feedback was effective to maintain the response to the initial education.

This is an open access article. 


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Antimicrobial resistance is a major challenge for modern healthcare.  The Duke Center for Antimicrobial Stewardship and Infection Prevention includes a unique portfolio of programs to fight this growing problem. We at CDC look forward to continuing our collaborations with Duke to help protect patients.

—Arjun Srinivasan, MD, FSHEA (CAPT, USPHS), Associate Director for Healthcare Associated Infection Prevention Programs, Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention

Dr Anderson and colleagues in the Duke Center for Antimicrobial Stewardship and Infection Prevention are world leaders in the important and essential fight to prevent infections and antimicrobial resistance. They are truly providing the 'guiding lights' and leadership  for all to follow in this mission.

—John Perfect, MD, Chief, Division of Infectious Diseases at Duke University School of Medicine

The Duke Center for Antimicrobial Stewardship and Infection Prevention is an important source for education and programmatic support for hospitals in the Southeastern US.  In addition, their research on the epidemiology of multidrug-resistant pathogens and enhancing antibiotic stewardship is of high quality and public health value.  I look forward to collaborating with Dr. Anderson and his expert colleagues for years to come.

—David Weber, MD, MPH, Medical Director of UNC Hospitals' Departments of Hospital Epidemiology and Occupational Health Service, Associate Chief Medical Officer of UNC Health Care