The DiRTE lab has three growing biorepositories of microbiological and stool specimens. Studies using these resources have focused on the molecular epidemiology of infection in academic and community hospitals. Overall, the biorepository has over 10,000 specimens, including 6,200 bacterial isolates and 3,300 C. difficile stool samples.
Since 2012, ten of the Duke Infection Control Outreach Network (DICON) hospitals have provided specimens from patients with multi-drug resistant organism and Clostridioides difficile infections. Our group currently collects microbiological and stool specimens from patients with MDRO infections in these community hospitals. The biorepository currently has more than 2,000 specimens, including more than 500 methicillin-resistant Staphylococcus aureus (MRSA) and 1,000 C. difficile isolates. Basic clinical data is retained on all patients whose specimens are collected.
Since 2018, all three Duke hospitals have provided stool specimens from patients with Clostridioides difficile infections. The biorepository currently has over 1,500 stool specimens. All clinical data is retained on patients whose specimens are collected.